An antiviral agent
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KIN101

Item No. 37429

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(4-bromophenyl)-7-[(methylsulfonyl)oxy]-4H-1-benzopyran-4-one
CAS Number
610753-87-2
Molecular Formula
C16H11BrO5S
Formula Weight
395.2
Purity
≥98%
Formulation (Request formulation change)
A neat solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 10 mg/ml
λmax
253 nm
SMILES
O=C1C(C2=CC=C(Br)C=C2)=COC3=CC(OS(=O)(C)=O)=CC=C13
InChi Code
InChI=1S/C16H11BrO5S/c1-23(19,20)22-12-6-7-13-15(8-12)21-9-14(16(13)18)10-2-4-11(17)5-3-10/h2-9H,1H3
InChi Key
SJGDYHHAYHRLNC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $101

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    10 mg

    $160

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    50 mg

    $651

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    100 mg

    $1,099

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    Cayman Chemical
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    Product Description

    KIN101 is an antiviral agent.1 It inhibits the replication of hepatitis C virus 2a (HCV2a) in Huh7 cells (EC50 = 0.2 µM). KIN101 (10 µM) reduces HCV2a RNA levels in infected Huh7 cells and influenza A nucleoprotein levels in infected MRC-5 cells. It increases the expression of innate immune response genes, including IRF3, the gene encoding the transcription factor interferon regulatory factor 3 (IRF3), in Sendai virus-infected MRC-5 cells when used at a concentration of 10 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bedard, K.M., Wang, M.L., Proll, S.C., et al. Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses. J. Virol. 86(13), 7334-7344 (2012).