An endogenous polyamine
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N8-Acetylspermidine (hydrochloride)

Item No. 37434

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[4-[(3-aminopropyl)amino]butyl]-acetamide, dihydrochloride
CAS Number
34450-15-2
Molecular Formula
C9H21N3O • 2HCl
Formula Weight
260.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly solubleMethanol: Slightly solubleWater: Soluble
SMILES
O=C(C)NCCCCNCCCN.Cl.Cl
InChi Code
InChI=1S/C9H21N3O.2ClH/c1-9(13)12-8-3-2-6-11-7-4-5-10;;/h11H,2-8,10H2,1H3,(H,12,13);2*1H
InChi Key
BWGUIRARVGYOIR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $49

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    10 mg

    $93

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    Product Description

    N8-Acetylspermidine is an endogenous polyamine.1,2,3 Urinary levels of N8-acetylspermidine are increased in patients with chronic pancreatitis.1 Blood levels of N8-acetylspermidine are increased in patients with ischemic cardiomyopathy, as well as in patients with Parkinson’s disease.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nissinen, S.I., Venalainen, M., Kumpulainen, P., et al. Discrimination between pancreatic cancer, pancreatitis and healthy controls using urinary polyamine panel. Cancer Control 29, 1-8 (2021).

    2. Saiki, S., Sasazawa, Y., Fujimaki, M., et al. A metabolic profile of polyamines in parkinson disease: A promising biomarker. Ann. Neurol. 86(2), 251-263 (2019).

    3. Nayak, A., Liu, C., Mehta, A., et al. N8-Acetylspermidine: A polyamine biomarker in ischemic cardiomyopathy with reduced ejection fraction. J. Am. Heart Assoc. 9(11), e016055 (2020).