A SARS-CoV-2 spike glycoprotein-derived peptide
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Spike Glycoprotein (1147-1162) (SARS-CoV-2, SARS-CoV) (trifluoroacetate salt)

Item No. 37491

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3S,6S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S)-9-((1H-imidazol-5-yl)methyl)-36-((S)-6-amino-2-((S)-2-((S)-2-amino-3-hydroxypropanamido)-3-phenylpropanamido)hexanamido)-12-(2-amino-2-oxoethyl)-15,24-bis(4-aminobutyl)-18-benzyl-33-(2-carboxyethyl)-27-(carboxymethyl)-21-(4-hydroxybenzyl)-6-((R)-1-hydroxyethyl)-3-(hydroxymethyl)-1-((S)-1-hydroxypyrrolidin-2-yl)-30-isobutyl-1,2,5,8,11,14,17,20,23,26,29,32,35-tridecaoxo-4,7,10,13,16,19,22,25,28,31,34-undecaazanonatriacontan-39-oic acid, trifluoroacetate salt
Synonyms
  • Surface Glycoprotein (1147-1162)
Molecular Formula
C90H132N22O28 • XCF3COOH
Formula Weight
1970.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Peptide Sequence
SFKEELDKYFKNHTSP-OH
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
OC(C(F)(F)F)=O.[H]N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CO)C(N1CCC[C@H]1C(O)=O)=O)=O)=O)CC2=CN=CN2)=O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=C(O)C=C4)=O)=O)CC(O)=O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O
InChi Code
InChI=1S/C90H132N22O28.C2HF3O2/c1-48(2)37-61(104-80(129)60(30-32-72(120)121)102-79(128)59(29-31-71(118)119)101-76(125)56(21-10-13-33-91)98-82(131)62(103-75(124)55(94)45-113)38-50-17-6-4-7-18-50)81(130)109-67(43-73(122)123)86(135)100-57(22-11-14-34-92)77(126)105-64(40-52-25-27-54(116)28-26-52)84(133)106-63(39-51-19-8-5-9-20-51)83(132)99-58(23-12-15-35-93)78(127)108-66(42-70(95)117)85(134)107-65(41-53-44-96-47-97-53)87(136)111-74(49(3)115)88(137)110-68(46-114)89(138)112-36-16-24-69(112)90(139)140;3-2(4,5)1(6)7/h4-9,17-20,25-28,44,47-49,55-69,74,113-116H,10-16,21-24,29-43,45-46,91-94H2,1-3H3,(H2,95,117)(H,96,97)(H,98,131)(H,99,132)(H,100,135)(H,101,125)(H,102,128)(H,103,124)(H,104,129)(H,105,126)(H,106,133)(H,107,134)(H,108,127)(H,109,130)(H,110,137)(H,111,136)(H,118,119)(H,120,121)(H,122,123)(H,139,140);(H,6,7)/t49-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,69+,74+;/m1./s1
InChi Key
SYSWUFOYPDJYJQ-YRTDBRIQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Spike glycoprotein (1147-1162) is a peptide corresponding to amino acids 1147-1162 of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, also known as the surface glycoprotein.1 This peptide is conserved across SARS-CoV, SARS-CoV-2, and various SARS-CoV-2 variants, including B.1.1.7, B.1.1.298, B.1.429, P.2, P.2, B.1.351, and B.1.617.2 and antibodies against this peptide neutralize SARS-CoV-2 and SARS-CoV pseudovirus particles in cellular assays.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, T., Kan, Q., Ge, J., et al. A novel linear and broadly neutralizing peptide in the SARS-CoV-2 S2 protein for universal vaccine development. Cell. Mol. Immunol. 18(11), 2563-2565 (2021).