An antimicrobial peptide
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RW4 (trifluoroacetate salt)

Item No. 37494

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-arginyl-L-tryptophyl-L-arginyl-L-tryptophyl-L-arginyl-L-tryptophyl-L-arginyl-L-tryptophanamide, trifluoroacetate salt
Synonyms
  • Arg-Trp-Arg-Trp-Arg-Trp-Arg-Trp-NH2
  • (RW)4-NH2
Molecular Formula
C68H91N25O8 • XCF3COOH
Formula Weight
1386.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Peptide Sequence
RWRWRWRW-NH2
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
NC([C@H](CC1=CNC2=CC=CC=C12)NC([C@H](CCCNC(N)=N)NC([C@H](CC3=CNC4=CC=CC=C34)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H](N)CCCNC(N)=N)=O)CC5=CNC6=CC=CC=C56)=O)=O)CC7=CNC8=CC=CC=C78)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C68H91N25O8.C2HF3O2/c69-45(17-9-25-79-65(71)72)58(95)91-54(30-38-34-84-47-19-6-2-14-42(38)47)62(99)88-51(23-11-27-81-67(75)76)60(97)93-56(32-40-36-86-49-21-8-4-16-44(40)49)64(101)89-52(24-12-28-82-68(77)78)61(98)92-55(31-39-35-85-48-20-7-3-15-43(39)48)63(100)87-50(22-10-26-80-66(73)74)59(96)90-53(57(70)94)29-37-33-83-46-18-5-1-13-41(37)46;3-2(4,5)1(6)7/h1-8,13-16,18-21,33-36,45,50-56,83-86H,9-12,17,22-32,69H2,(H2,70,94)(H,87,100)(H,88,99)(H,89,101)(H,90,96)(H,91,95)(H,92,98)(H,93,97)(H4,71,72,79)(H4,73,74,80)(H4,75,76,81)(H4,77,78,82);(H,6,7)/t45-,50-,51-,52-,53-,54-,55-,56-;/m0./s1
InChi Key
DNIVTCIDABYXHY-YPAVPXSJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    RW4 is an antimicrobial peptide.1 It is active against E. coli and S. aureus (IC50s = 9.6 and 5.1 µM, respectively). RW4 also induces hemolysis of isolated ovine erythrocytes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, Z., Brady, A., Young, A., et al. Length effects in antimicrobial peptides of the (RW)n series. Antimicrob. Agents Chemother. 51(2), 597-603 (2007).