Produced from 11Z,14Z-eicosadienoic acid by COX in a lipoxygenase-type reaction
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Isomer(s)
37500(±)11-HEDE
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11(R)-HEDE

Item No. 37505

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
11R-hydroxy-12E,14Z-eicosadienoic acid
CAS Number
330800-88-9
Molecular Formula
C20H36O3
Formula Weight
324.5
Purity
≥98%
Formulation (Request formulation change)
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/mlPBS pH 7.2: 1 mg/ml
λmax
234 nm
SMILES
CCCCC/C=C\C=C\[C@H](O)CCCCCCCCCC(O)=O
InChi Code
InChI=1S/C20H36O3/c1-2-3-4-5-7-10-13-16-19(21)17-14-11-8-6-9-12-15-18-20(22)23/h7,10,13,16,19,21H,2-6,8-9,11-12,14-15,17-18H2,1H3,(H,22,23)/b10-7-,16-13+/t19-/m0/s1
InChi Key
HDMIRVFIVOGVIC-VOYJXKAKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    25 µg

    $129

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    50 µg

    $168

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    100 µg

    $281

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    250 µg

    $636

    Add
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    Product Description

    11(R)-HEDE is produced from 11Z,14Z-eicosadienoic acid by COX in a lipoxygenase-type reaction.1 Spectrophotometric measurement of the conjugated diene absorbance of 11(R)-HEDE is occasionally used to quantify COX activity.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hemler, M.E., Crawford, C.G., and Lands, W.E.M. Lipoxygenation activity of purified prostaglandin-forming cyclooxygenase. Biochemistry 17(9), 1772-1779 (1978).

    2. Koshkin, V., and Dunford, H.B. Reaction of prostaglandin endoperoxide synthase with cis,cis-eicosa-11,14-dienoic acid. The Journal of Biological Chemisty 273, 6046-6049 (1998).