A flavonoid with diverse biological activities
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Camellianin A

Item No. 37575

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-[[6-O-acetyl-4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CAS Number
109232-77-1
Molecular Formula
C29H32O15
Formula Weight
620.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly Soluble: 0.1-1 mg/mlDMSO: Sparingly Soluble: 1-10 mg/mlMethanol: Slightly Soluble: 0.1-1 mg/mlWater: Slightly Soluble: 0.1-1 mg/ml
SMILES
O=C1C=C(C2=CC=C(C=C2)O)OC3=CC(O)=CC(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O)COC(C)=O)=C31
InChi Code
InChI=1S/C29H32O15/c1-11-22(34)23(35)25(37)28(40-11)44-27-20(10-39-12(2)30)43-29(26(38)24(27)36)42-19-8-15(32)7-18-21(19)16(33)9-17(41-18)13-3-5-14(31)6-4-13/h3-9,11,20,22-29,31-32,34-38H,10H2,1-2H3/t11-,20+,22-,23+,24+,25+,26+,27+,28-,29+/m0/s1
InChi Key
RHJULGLSOARXMO-YXRGHUGASA-N
Origin
Plant/Oil tea
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $87

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    5 mg

    $261

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    10 mg

    $435

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    Product Description

    Camellianin A is a flavonoid that has been found in A. nitida and has diverse biological activities.1,1,2 It inhibits angiotensin-converting enzyme (ACE) by 30.16% when used at a concentration of 500 µg/ml.1 Camellianin A (200 µM) induces cell cycle arrest at the G1 phase and apoptosis in HepG2 and MCF-7 cancer cells.1 In vivo, camellianin A (30 mg/kg) reduces hepatocyte apoptosis, as well as hepatic TNF-α, IL-6, IL-1β, and malondialdehyde (MDA) levels, in a mouse model of carbon tetrachloride-induced liver injury.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, B., Yang, J., Ma, Y., et al. Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids from Adinandra nitida leaves. Pharm. Biol. 48(12), 1432-1438 (2010).

    2. Chen, R., Lian, Y., Wen, S., et al. Shibi tea (Adinandra nitida) and camellianin a alleviate CCl4-induced liver injury in C57BL-6J mice by attenuation of oxidative stress, inflammation, and apoptosis. Nutrients 14(15), 3037 (2022).