An inhibitor of DGAT-1
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CAY10794

Item No. 37585

Technical Information
Formal Name
N-[4-[(2-methoxyethyl)methylamino]phenyl]-2-phenyl-5-(trifluoromethyl)-4-oxazolecarboxamide
CAS Number
1231243-91-6
Molecular Formula
C21H20F3N3O3
Formula Weight
Purity
≥98%
Formulation
A solid
DMF: 3 mg/mlDMSO: 2 mg/mlEthanol: Slightly solublePBS (pH 7.2): 0.2 mg/ml
λmax
257 nm
SMILES
O=C(C1=C(C(F)(F)F)OC(C2=CC=CC=C2)=N1)NC3=CC=C(N(CCOC)C)C=C3
InChi Code
InChI=1S/C21H20F3N3O3/c1-27(12-13-29-2)16-10-8-15(9-11-16)25-19(28)17-18(21(22,23)24)30-20(26-17)14-6-4-3-5-7-14/h3-11H,12-13H2,1-2H3,(H,25,28)
InChi Key
GLLFNZDVMSLOCL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    CAY10794 is an inhibitor of diacylglycerol acyltransferase 1 (DGAT-1; IC50 = 0.325 µM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Qian, Y., Wertheimer, S.J., Ahmad, M., et alDiscovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes. J. Med. Chem. 54(7), 2433-2446 (2011).