A calcium ionophore
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Product Type

Biochemicals

Research Area

Calcium Ionophore II

Item No. 37707

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2′-oxybis[N,N-dicyclohexyl-acetamide]
CAS Number
74267-27-9
Synonyms
  • ETH 129
Molecular Formula
C28H48N2O3
Formula Weight
460.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: 1 mg/ml
SMILES
O=C(COCC(N(C1CCCCC1)C2CCCCC2)=O)N(C3CCCCC3)C4CCCCC4
InChi Code
InChI=1S/C28H48N2O3/c31-27(29(23-13-5-1-6-14-23)24-15-7-2-8-16-24)21-33-22-28(32)30(25-17-9-3-10-18-25)26-19-11-4-12-20-26/h23-26H,1-22H2
InChi Key
URAUKAJXWWFQSU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $37

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    10 mg

    $70

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    25 mg

    $163

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    50 mg

    $289

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    Product Description

    Calcium ionophore II is a neutral calcium ionophore.1 It is selective for calcium over strontium, manganese, cobalt, nickel, zinc, lanthanum, sodium, potassium, and magnesium. Calcium ionophore II binds to calcium in a 1:3 (ligand:ion) ratio and induces calcium transport across artificial membranes and into rat liver mitochondria.2 It induces sea urchin egg activation when used at a concentration of 100 pM. Calcium ionophore II has been used in the preparation of calcium-selective electrodes.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wang, E., Erdahl, W.L., Hamidinia, S.A., et al. Transport properties of the calcium ionophore ETH-129. Biophys J. 81(6), 3275-3284 (2001).

    2. Prestipino, G., Falugi, C., Falchetto, R., et al. The ionophore ETH 129 as Ca2+ translocator in artificial and natural membranes. Anal. Biochem. 210(1), 119-122 (1993).

    3. Park, S., Maier, C.S., and Koley, D. Anodic stripping voltammetry on a carbon-based ion-selective electrode. Electrochim. Acta 390, 138855 (2021).