A dual LH and TSH receptor agonist
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

ORG 41841

Item No. 37724

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-amino-N-(1,1-dimethylethyl)-4-(3-methoxyphenyl)-2-(methylthio)-thieno[2,3-d]pyrimidine-6-carboxamide
CAS Number
301847-37-0
Molecular Formula
C19H22N4O2S2
Formula Weight
402.5
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: Slightly solubleEthanol: Slightly soluble
λmax
218, 242, 303 nm
SMILES
O=C(C1=C(N)C2=C(C3=CC(OC)=CC=C3)N=C(SC)N=C2S1)NC(C)(C)C
InChi Code
InChI=1S/C19H22N4O2S2/c1-19(2,3)23-16(24)15-13(20)12-14(10-7-6-8-11(9-10)25-4)21-18(26-5)22-17(12)27-15/h6-9H,20H2,1-5H3,(H,23,24)
InChi Key
DVSFSADBOJYPGF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $54

    Add

    5 mg

    $244

    Add

    10 mg

    $432

    Add

    25 mg

    $943

    Add
    Product Description

    ORG 41841 is a dual luteinizing hormone (LH) and thyroid-stimulating hormone (TSH) receptor agonist.1 It induces cAMP production in HEK293 cells expressing human LH or TSH receptors (EC50s = 0.3 and 6.5 µM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Moore, A., Jaeschke, H., Kleinau, G., et al. Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: Structure-activity relationships and selective binding patterns. J. Med. Chem. 49(13), 3888-3896 (2006).