A disaccharide microbial metabolite with diverse biological activities
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Lentztrehalose B

Item No. 37733

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α-D-glucopyranosyl 4-O-(3-methyl-2-buten-1-yl)-α-D-glucopyranoside
CAS Number
1808096-67-4
Molecular Formula
C17H30O11
Formula Weight
410.4
Purity
≥80%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleMethanol: SolubleWater: Soluble
SMILES
C/C(C)=C/CO[C@@H]1[C@H](O[C@@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)CO
InChi Code
InChI=1S/C17H30O11/c1-7(2)3-4-25-15-9(6-19)27-17(14(24)12(15)22)28-16-13(23)11(21)10(20)8(5-18)26-16/h3,8-24H,4-6H2,1-2H3/t8-,9-,10-,11+,12-,13-,14-,15-,16-,17-/m1/s1
InChi Key
NODZOHVOYATRLP-JFQXGGNQSA-N
Origin
Bacterium/Lentzea sp. ML457-mF8
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    10 mg

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    Product Description

    Lentztrehalose B is a disaccharide microbial metabolite that has been found in Lentzea and has diverse biological activities.1 It has antioxidant activity in an oxygen radical absorbance capacity (ORAC) assay when used at a concentration of 100 µM. Lentztrehalose B (10 mM) inhibits the activity of porcine kidney trehalase, the trehalose metabolizing enzyme. It induces autophagy in MeWo melanoma and OVK18 ovarian cancer cells when used at a concentration of 100 mM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wada, S., Kubota, Y., Sawa, R., et al. Novel autophagy inducers lentztrehaloses A, B and C. J. Antibiot. (Tokyo) 68(8), 521-529 (2015).