A fluorenone and DPP-3 inhibitor
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Fluostatin B

Item No. 37771

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,3-dihydro-1,2,6,7-tetrahydroxy-3-methyl-1H-benzo[a]fluorene-4,11-dione
CAS Number
158906-40-2
Molecular Formula
C18H14O6
Formula Weight
326.3
Purity
≥90%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetone: Slightly solubleDMSO: SolubleEthyl Acetate: Slightly soluble
SMILES
O=C1C2=C(C3=C1C4=C(C(C(C(C4O)O)C)=O)C=C3O)C(O)=CC=C2
InChi Code
InChI=1S/C18H14O6/c1-6-15(21)8-5-10(20)13-11-7(3-2-4-9(11)19)17(23)14(13)12(8)18(24)16(6)22/h2-6,16,18-20,22,24H,1H3
InChi Key
PLKATXVLQJQTSA-UHFFFAOYSA-N
Origin
Bacterium/Streptomyces sp. TA-3391
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $556

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    Product Description

    Fluostatin B is a fluorenone originally found in Streptomyces.1 It inhibits dipeptidyl peptidase 3 (DPP-3; IC50 = 24 µg/ml).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Akiyama, T., Harada, S., Kojima, F., et al. Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. I. Taxonomy of producing strain, production, isolation, physico-chemical properties and biological properties. J. Antibiot. (Tokyo) 51(6), 553-559 (1998).