A naphthoquinone and GSTP1 inhibitor
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Bequinostatin A

Item No. 37772

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(–)-5,6,8,13-tetrahydro-1,6,7,9,11-pentahydroxy-8,13-dioxo-3-pentyl-benzo[a]naphthacene-2-carboxylic acid
CAS Number
151013-37-5
Molecular Formula
C28H24O9
Formula Weight
504.5
Purity
≥75%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleMethanol: SolublePyridine: Soluble
SMILES
OC1=C2C3=CC(C(C4=CC(O)=CC(O)=C4C5=O)=O)=C5C(O)=C3C(CC2=CC(CCCCC)=C1C(O)=O)O
InChi Code
InChI=1S/C28H24O9/c1-2-3-4-5-11-6-12-7-17(30)21-14(19(12)25(33)20(11)28(36)37)10-16-23(26(21)34)27(35)22-15(24(16)32)8-13(29)9-18(22)31/h6,8-10,17,29-31,33-34H,2-5,7H2,1H3,(H,36,37)
InChi Key
RKXRXHADKSOULC-UHFFFAOYSA-N
Origin
Bacterium/Streptomyces sp. MI384-DF12
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $516

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    Product Description

    Bequinostatin A is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC50 = 0.6 µg/ml for human GSTP1).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aoyama, T., Kojima, F., Abe, F., et al. Bequinostatins A and B new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities. J. Antibiot. (Tokyo) 46(6), 914-920 (1993).