A naphthoquinone and GSTP1 inhibitor
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Bequinostatin C

Item No. 37773

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
8,13-dihydro-1,7,9,11-tetrahydroxy-8,13-dioxo-3-pentyl-benzo[a]naphthacene-2-carboxylic acid
CAS Number
152175-74-1
Molecular Formula
C28H22O8
Formula Weight
486.5
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly solubleMethanol: Slightly soluble
SMILES
O=C(C1=C(C(C(C=C1CCCCC)=CC=C2C(O)=C3C(C4=C(C=C(C=C45)O)O)=O)=C2C=C3C5=O)O)O
InChi Code
InChI=1S/C28H22O8/c1-2-3-4-5-12-8-13-6-7-15-16(20(13)26(33)21(12)28(35)36)11-18-23(25(15)32)27(34)22-17(24(18)31)9-14(29)10-19(22)30/h6-11,29-30,32-33H,2-5H2,1H3,(H,35,36)
InChi Key
NJGDHHRUAFIFFQ-UHFFFAOYSA-N
Origin
Bacterium/Streptomyces sp. MI384-DF12
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $516

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    Product Description

    Bequinostatin C is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC50 = 40 µg/ml for human GSTP1).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yamazaki, T., Tatee, T., Aoyama, T., et al. Bequinostatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. J. Antibiot. (Tokyo) 46(8), 1309-1311 (1993).