A Cdc42 inhibitor
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CID-44216842

Item No. 37775

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[5-(4-bromophenyl)-4,5-dihydro-3-(3-methoxyphenyl)-1H-pyrazol-1-yl]-benzenesulfonamide
CAS Number
1222513-26-9
Molecular Formula
C22H20BrN3O3S
Formula Weight
486.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
λmax
358 nm
SMILES
NS(C(C=C1)=CC=C1N2C(C3=CC=C(Br)C=C3)CC(C4=CC(OC)=CC=C4)=N2)(=O)=O
InChi Code
InChI=1S/C22H20BrN3O3S/c1-29-19-4-2-3-16(13-19)21-14-22(15-5-7-17(23)8-6-15)26(25-21)18-9-11-20(12-10-18)30(24,27)28/h2-13,22H,14H2,1H3,(H2,24,27,28)
InChi Key
LPUYDLXQQMWRLR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $44

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    5 mg

    $208

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    10 mg

    $329

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    25 mg

    $493

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    Product Description

    CID-44216842 is a cell division cycle 42 (Cdc42) inhibitor.1 It inhibits GTP binding to wild-type Cdc42 and the constitutively active mutant Cdc42Q61L (EC50s = 0.3 and 0.5 µM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hong, L., Kenney, S.R., Phillips, G.K., et al. Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. The Journal of Biological Chemisty 288(12), 8531-8543 (2013).