A bile acid sequestrant
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Cholestyramine

Item No. 37827

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
11041-12-6
Formulation (Request formulation change)
A solid
SMILES
C[N+](C)(C)CC(C=C1)=CC=C1C(CC)CC(C2=CC=CC=C2)CC.CCC(C)C.[Cl-]
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $54

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    Product Description

    Cholestyramine is a bile acid sequestrant.1 It binds to bile acids in the intestine and inhibits their absorption, which increases the synthesis of bile acids from cholesterol in the liver, thereby lowering serum LDL levels. Cholestyramine reduces serum cholesterol levels and increases bile acid excretion in the feces without changing the bile acid pool size in rabbits.2 Formulations containing cholestyramine have been used as adjuncts in the treatment of primary hypercholesterolemia.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Scaldaferri, F., Pizzoferrato, M., Ponziani, F.R., et al. Use and indications of cholestyramine and bile acid sequestrants. Intern. Emerg. Med. 8(3), 205-210 (2013).

    2. Qiu, D.N., Shang, Q., Sun, D.Y., et al. Cholestyramine alters bile acid amounts and the expression of cholesterol-related genes in rabbit intestinal and hepatic tissues. J. Dig. Dis. 18(2), 107-114 (2017).