An ionizable cationic lipid
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OF-Deg-Lin

Item No. 37853

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9Z,12Z-octadecadienoic acid, 1,1′,1′′,1′′′-[(3,6-dioxo-2,5-piperazinediyl)bis(4,1-butanediylnitrilodi-2,1-ethanediyl)] ester
CAS Number
1853202-95-5
Molecular Formula
C92H160N4O10
Formula Weight
1482.3
Purity
≥90%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Ethanol: Soluble
SMILES
O=C(NC(C(N1)=O)CCCCN(CCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)C1CCCCN(CCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O
InChi Code
InChI=1S/C92H160N4O10/c1-5-9-13-17-21-25-29-33-37-41-45-49-53-57-61-71-87(97)103-81-77-95(78-82-104-88(98)72-62-58-54-50-46-42-38-34-30-26-22-18-14-10-6-2)75-67-65-69-85-91(101)94-86(92(102)93-85)70-66-68-76-96(79-83-105-89(99)73-63-59-55-51-47-43-39-35-31-27-23-19-15-11-7-3)80-84-106-90(100)74-64-60-56-52-48-44-40-36-32-28-24-20-16-12-8-4/h21-28,33-40,85-86H,5-20,29-32,41-84H2,1-4H3,(H,93,102)(H,94,101)/b25-21-,26-22-,27-23-,28-24-,37-33-,38-34-,39-35-,40-36-
InChi Key
HAZAXVJMCWCIDS-RGLFHLPNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $82

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    5 mg

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    10 mg

    $647

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    Cayman Chemical
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    Product Description

    OF-Deg-Lin is an ionizable cationic lipid.1 It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rissanou, A.N., and Karatasos, K. Effects of the structure of lipid-based agents in their complexation with a single stranded mRNA fragment: A computational study. Soft Matter 18(33), 6229-6245 (2022).