A synthetic bioactive sphingolipid
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Alternative(s)
22510Sphinganine (d17:0)
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Sphinganine (d17:0) (hydrochloride)

Item No. 37989

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2S-amino-1,3R-heptadecanediol, monohydrochloride
Synonyms
  • D-erythro-C17-Dihydrosphingosine
  • D-erythro-Sphinganine C-17
Molecular Formula
C17H37NO2 • HCl
Formula Weight
323.9
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 2 mg/ml
SMILES
OC[C@H](N)[C@H](O)CCCCCCCCCCCCCC.Cl
InChi Code
InChI=1S/C17H37NO2.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19;/h16-17,19-20H,2-15,18H2,1H3;1H/t16-,17+;/m0./s1
InChi Key
GJGQRCHDXLYMRD-MCJVGQIASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $96

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    1 mg

    $163

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    Product Description

    Sphinganine (d17:0) is a synthetic bioactive sphingolipid.1 It is active against C. glabrata and C. albicans with a minimum fungicidal concentration (MFC) value of 0.5 µg/ml for both. Sphinganine (d17:0) has commonly been used as an internal standard for the detection of sphingolipids in chromatographic and mass spectrometry applications.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Thevissen, K., Hillaert, U., Meert, E.M., et al. Fungicidal activity of truncated analogues of dihydrosphingosine. Bioorg. Med. Chem. Lett. 18(13), 3728-3730 (2008).

    2. Spassieva, S., Bielawski, J., Anelli, V., et al. Combination of C17 sphingoid base homologues and mass spectrometry analysis as a new approach to study sphingolipid metabolism. Methods Enzymol. 434, 233-241 (2007).

    3. Qu, F., Wu, C.S., Hou, J.F., et al. Sphingolipids as new biomarkers for assessment of delayed-type hypersensitivity and response to triptolide. PLoS One 7(12), e52454 (2012).