A lipase inhibitor
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Ethyl HDFP

Item No. 38209

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
p-hexadecyl-phosphonofluoridic acid, ethyl ester
CAS Number
1407160-81-9
Synonyms
  • Ethyl Hexadecylfluorophosphonate
  • Ethyl P-Hexadecylphosphonofluoridate
Molecular Formula
C18H38FO2P
Formula Weight
336.5
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/ml
SMILES
CCCCCCCCCCCCCCCCP(OCC)(F)=O
InChi Code
InChI=1S/C18H38FO2P/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(19,20)21-4-2/h3-18H2,1-2H3
InChi Key
BBACYOMDPVSVIS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $40

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    5 mg

    $187

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    10 mg

    $355

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    Product Description

    Ethyl HDFP is a lipase inhibitor.1 It inhibits 12 lipases, including fatty acid amide hydrolase (FAAH), fatty acid synthase (FASN), and α/β-hydrolase domain-containing protein 4 (ABHD4), by greater than 75% in mouse T cell hybridoma lysates when used at a concentration of 2 µM. Ethyl HDFP inhibits depalmitoylation of H-Ras in HEK293 cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Martin, B.R., Wang, C., Adibekian, A., et al. Gobal pofiling of dynamic protein palmitoylation. Nat. Methods 9(1), 84-89 (2012).