An ionizable cationic lipid
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1,2-Dipalmitoyl-3-dimethylammonium-propane

Item No. 38311

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
hexadecanoic acid, 1,1′-[1-[(dimethylamino)methyl]-1,2-ethanediyl] ester
CAS Number
96326-74-8
Synonyms
  • 16:0 DAP
  • DPDAP
Molecular Formula
C37H73NO4
Formula Weight
596.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Soluble
SMILES
CN(C)CC(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C37H73NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36(39)41-34-35(33-38(3)4)42-37(40)32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h35H,5-34H2,1-4H3
InChi Key
ALRIWCIIGVAXHV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $46

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    Product Description

    1,2-Dipalmitoyl-3-dimethylammonium-propane (DPDAP) is an ionizable cationic lipid that has been used in the generation of liposomes for the delivery of miRNA.1 Liposomes containing DPDAP and encapsulating miR-21, miR-324, and scramble miRNA increase axonogenesis of mouse trigeminal ganglion neurons.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Amit, M., Takahashi, H., Dragomir, M.P., et al. Loss of p53 drives neuron reprogramming in head and neck cancer. Nature 578(7795), 449-454 (2020).