An amine-modified nucleotide
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5-(3-Aminoallyl)-2'-deoxyuridine-5'-O-triphosphate (sodium salt)

Item No. 38361

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-(3-amino-1-propen-1-yl)-2′-deoxy-uridine 5′-(tetrahydrogen triphosphate), tetrasodium salt
CAS Number
85280-65-5
Synonyms
  • AA-dUTP
  • aminoallyl-dUTP
Molecular Formula
C12H16N3O14P3 • 4Na
Formula Weight
611.2
Purity
≥98%
Formulation (Request formulation change)
A solution in water
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
O[C@@H]1[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@@H](N2C(NC(C(/C=C/CN)=C2)=O)=O)C1.[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C12H20N3O14P3.4Na/c13-3-1-2-7-5-15(12(18)14-11(7)17)10-4-8(16)9(27-10)6-26-31(22,23)29-32(24,25)28-30(19,20)21;;;;/h1-2,5,8-10,16H,3-4,6,13H2,(H,22,23)(H,24,25)(H,14,17,18)(H2,19,20,21);;;;/q;4*+1/p-4/b2-1+;;;;/t8-,9+,10+;;;;/m0..../s1
InChi Key
RYISGISBPJBEJG-YLUGEOHISA-J
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    2.6 mg

    $388

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    Product Description

    5-(3-Aminoallyl)-2'-deoxyuridine-5'-O-triphosphate (aminoallyl-dUTP) is an amine-modified nucleotide that has been used in the synthesis of fluorescently labeled dUTP.1 Incorporation of aminoallyl-dUTP into primers has been used in the generation of fluorescently labeled probes for DNA microarrays and FRET-based assays to measure the activity of reverse transcriptases.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kuznetsova, V.E., Spitsyn, M.A., Shershov, V.E., et al. Novel fluorescently labeled nucleotides: Synthesis, spectral properties and application in polymerase chain reaction. Mendeleev Commun. 26(2), 95-98 (2016).

    2. Xiang, C.C., Kozhich, O.A., Chen, M., et al. Amine-modified random primers to label probes for DNA microarrays. Nat. Biotechnol. 20(7), 738-742 (2002).

    3. Krebs, J.F., and Kore, A.R. Novel FRET-based assay to detect reverse transcriptase activity using modified dUTP analogues. Bioconjug. Chem. 19(1), 185-191 (2008).