An amine-modified nucleotide
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3'-Amino-3'-deoxyadenosine-5'-O-triphosphate (sodium salt)

Item No. 38364

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3′-amino-3′-deoxy-adenosine 5′-(tetrahydrogen triphosphate), tetrasodium salt
Synonyms
  • 3'-Deoxy-3'-amino ATP
  • 3'-NH2-dATP
Molecular Formula
C10H13N6O12P3 • 4Na
Formula Weight
594.1
Purity
≥98%
Formulation (Request formulation change)
A 10 mM solution in water
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
N[C@@H]1[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]1O.[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C10H17N6O12P3.4Na/c11-5-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(5)17)16-3-15-6-8(12)13-2-14-9(6)16;;;;/h2-5,7,10,17H,1,11H2,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20);;;;/q;4*+1/p-4/t4-,5-,7-,10-;;;;/m1..../s1
InChi Key
JSEBFJJFFVUXAX-RBLJNHJVSA-J
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    2.5 mg

    $478

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    Product Description

    3'-Amino-3'-deoxyadenosine-5'-O-triphosphate is an amine-modified nucleotide that has been used as a probe for quantifying ATP substrate specificity of kinases and ligases.1 It terminates RNA strand synthesis catalyzed by RNA polymerase in E. coli.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kinoshita, Y., and Nishigaki, K. Unexpectedly general replaceability of ATP in ATP-requiring enzymes. J. Biochem. 122(1), 205-211 (1997).

    2. Kutateladze, T., Beabealashvili, R., Azhayev, A., et al. 3'-deoxy-3'-aminonucleoside 5'-triphosphates — terminators of RNA synthesis, catalyzed by DNA-dependent RNA polymerase from Escherichia coli. FEBS Lett. 153(2), 420-426 (1983).