An inhibitor of alkaline phosphatase
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β-Glycerophosphate (sodium salt hydrate)

Item No. 38367

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,2,3-propanetriol, 2-(dihydrogen phosphate), disodium salt, pentahydrate
CAS Number
13408-09-8
Synonyms
  • Glycerol 2-Phosphate
Molecular Formula
C3H7O6P • 2Na [5H2O]
Formula Weight
306.1
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
[O-]P(OC(CO)CO)([O-])=O.[Na+].[Na+].O.O.O.O.O
InChi Code
InChI=1S/C3H9O6P.2Na.5H2O/c4-1-3(2-5)9-10(6,7)8;;;;;;;/h3-5H,1-2H2,(H2,6,7,8);;;5*1H2/q;2*+1;;;;;/p-2
InChi Key
PEMUISUYOHQFQH-UHFFFAOYSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $31

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    5 g

    $77

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    Product Description

    β-Glycerophosphate is an inhibitor of alkaline phosphatase (ALP).1 It decreases ALP activity and promotes bone mineralization in chick osteoblasts when used at concentrations of 10 and 20 mM. β-Glycerophosphate (10 mM) induces calcification of cultured bovine vascular smooth muscle cells (BVSMCs) in an ALP-dependent manner.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chung, C.H., Golub, E.E., Forbes, E., et al. Mechanism of action on β-glycerophosphate on bone cell mineralization. Calcif. Tissue Int. 51(4), 305-311 (1992).

    2. Shioi, A., Nishizawa, Y., Jono, S., et al. β-Glycerophosphate accelerates calcification in cultured bovine vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 15(11), 2003-2009 (1995).