An inhibitor of ecto-5’-nucleotidase
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Cytidine 5'-methylenediphosphate (sodium salt)

Item No. 38372

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
cytidine, 5′-[hydrogen P-(phosphonomethyl)phosphonate], trisodium salt
Synonyms
  • CBP
  • CMP-CP
  • Cytidine-5'-O-(α,β-methylene)diphosphate
Molecular Formula
C10H14N3O10P2 • 3Na
Formula Weight
467.2
Purity
≥95%
Formulation (Request formulation change)
A solution in water
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
O=C1N=C(N)C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP([O-])(CP([O-])([O-])=O)=O)O2.[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C10H17N3O10P2.3Na/c11-6-1-2-13(10(16)12-6)9-8(15)7(14)5(23-9)3-22-25(20,21)4-24(17,18)19;;;/h1-2,5,7-9,14-15H,3-4H2,(H,20,21)(H2,11,12,16)(H2,17,18,19);;;/q;3*+1/p-3/t5-,7-,8-,9-;;;/m1.../s1
InChi Key
NCIMPWGFHADYTQ-WKMNQBAXSA-K
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    2 mg

    $224

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    Product Description

    Cytidine 5'-methylenediphosphate is an inhibitor of ecto-5'-nucleotidase, also known as CD73 (Ki = 898 nM), an enzyme that converts AMP to adenosine.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Junker, A., Renn, C., Dobelmann, C., et al. Structure-activity relationship of purine and pyrimidine nucleotides as ecto-5'-nucleotidase (CD73) inhibitors. J. Med. Chem. 62(7), 3677-3695 (2019).