A fluorescent derivative of NADP+
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ε-NADP+ (sodium salt)

Item No. 38387

Technical Information
Formal Name
(2R,3R,4R,5R)-5-((((((((2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)oxidophosphoryl)oxy)oxidophosphoryl)oxy)methyl)-4-hydroxy-2-(3H-imidazo[2,1-i]purin-3-yl)tetrahydrofuran-3-yl phosphate, trisodium salt
Synonyms
  • N6-Ethenoadenine dinucleotide phosphate
  • β-Nicotinamide-1
  • ε-Nicotinamide adenine dinucleotide phosphate
Molecular Formula
C23H25N7O17P3 • 3Na
Formula Weight
Purity
≥95%
Emission
400 nm
Excitation
310 nm
A solid
Water: Soluble
SMILES
O[C@H]([C@H](O[C@H]1N2C3=C(N=C2)C4=NC=CN4C=N3)COP([O-])(OP([O-])(OC[C@H]([C@H]([C@H]5O)O)O[C@H]5[N+]6=CC(C(N)=O)=CC=C6)=O)=O)[C@H]1OP([O-])([O-])=O.[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C23H28N7O17P3.3Na/c24-19(34)11-2-1-4-28(6-11)22-17(33)15(31)12(44-22)7-42-49(38,39)47-50(40,41)43-8-13-16(32)18(46-48(35,36)37)23(45-13)30-10-26-14-20-25-3-5-29(20)9-27-21(14)30;;;/h1-6,9-10,12-13,15-18,22-23,31-33H,7-8H2,(H5-,24,34,35,36,37,38,39,40,41);;;/q;3*+1/p-3/t12-,13-,15-,16-,17-,18-,22-,23-;;;/m1.../s1
InChi Key
GZOUKPXINNPDSG-JTYASKIASA-K
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    Product Description

    ε-NADP+ is a fluorescent derivative of the cofactor NADP+ (Item No. 10004675).1 ε-NADP+ displays an emission maximum of 400 upon excitation at 310 nm.1 ε-NADP+ has been used to determine the binding stoichiometry of NADP+ to fatty acid synthase (FASN).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wong, H., Mattick, J.S., and Wakil, S.J. The architecture of the animal fatty acid synthetase. III. Isolation and characterization of β-ketoacyl reductase. The Journal of Biological Chemisty 258(24), 15305-15311 (1983).