A fluorescent nucleotide derivative
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3'-O-Anthraniloyl- 2'-deoxyadenosine-5'-O-triphosphate (sodium salt)

Item No. 38442

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2′-deoxy-adenosine 5′-(tetrahydrogen triphosphate) 3′-(2-aminobenzoate), tetrasodium salt
Synonyms
  • ANT-dATP
  • ANT-deoxy ATP
Molecular Formula
C17H17N6O13P3 • 4Na
Formula Weight
698.2
Purity
≥95%
Emission
425 nm
Excitation
330 nm
Formulation (Request formulation change)
A solution in water
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
NC1=C(N=C2)C(N2[C@H]3C[C@H](OC(C4=C(N)C=CC=C4)=O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O3)=NC=N1.[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C17H21N6O13P3.4Na/c18-10-4-2-1-3-9(10)17(24)34-11-5-13(23-8-22-14-15(19)20-7-21-16(14)23)33-12(11)6-32-38(28,29)36-39(30,31)35-37(25,26)27;;;;/h1-4,7-8,11-13H,5-6,18H2,(H,28,29)(H,30,31)(H2,19,20,21)(H2,25,26,27);;;;/q;4*+1/p-4/t11-,12+,13+;;;;/m0..../s1
InChi Key
ITCVLNLPDKLCLC-NDASMTADSA-J
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    600 µg

    $208

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    Product Description

    3'-O-Anthraniloyl-2'-deoxyadenosine-5'-O-triphosphate is a fluorescent nucleotide derivative.1 It displays an emission maximum of 425 nm upon excitation at 330 nm.{|Sarfati1990|} It inhibits B. pertussis and B. anthracis adenylyl cyclases (ACs; Kis = 9.1 and 8 µM, respectively). 3'-O-Anthraniloyl-2'-deoxyadenosine-5'-O-triphosphate has been used as a probe for binding sites in, and ion effects on the enzymatic activity of, B. pertussis and B. anthracis ACs.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sarfati, R.S., Kansal, V.K., Munier, H., et al. Binding of 3'-anthraniloyl-2'-deoxy-ATP to calmodulin-activated adenylate cyclase from Bordetella pertussis and Bacillus anthracis. The Journal of Biological Chemisty 265(31), 18902-18906 (1990).