A P2Y6 receptor agonist
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UDP-β-S (sodium salt)

Item No. 38493

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5′-uridylic acid, monoanhydride with phosphorothioic acid, trisodium salt
Synonyms
  • Uridine-5' O-(2-thiodiphosphate)
Molecular Formula
C9H11N2O11P2S • 3Na
Formula Weight
486.2
Purity
≥95%
Formulation (Request formulation change)
A solution in water
Solubility(Learn about Variance in Solubility)
Water: soluble
SMILES
O=C(N(C=C1)[C@H]2[C@H](O)[C@H](O)[C@@H](COP([O-])(OP([S-])([O-])=O)=O)O2)NC1=O.[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C9H14N2O11P2S.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(21-8)3-20-23(16,17)22-24(18,19)25;;;/h1-2,4,6-8,13-14H,3H2,(H,16,17)(H,10,12,15)(H2,18,19,25);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
InChi Key
FCPBZCVZMNISHS-LLWADOMFSA-K
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    2.1 mg

    $489

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    Product Description

    UDP-β-S is an agonist of the purinergic P2Y6 receptor.1 It selectively induces inositol phosphate accumulation in 1321N1 cells expressing P2Y6 receptors (EC50 = 28 nM) over those expressing P2Y1, P2Y2, or P2Y4 receptors at 10 µM. UDP-β-S (1 µM) induces DNA synthesis in isolated rat aorta smooth muscle cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hou, M., Harden, T.K., Kuhn, C.M., et al. UDP acts as a growth factor for vascular smooth muscle cells by activation of P2Y6 receptors. Am. J. Physiol. Heart Circ. Physiol. 282(2), H784-H792 (2002).