An Analytical Reference Standard
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Research Tool(s)
15949Clonidine (hydrochloride)
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Clonidine (hydrochloride)

Item No. 38558

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • ST 155
Technical Information
Formal Name
N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride
CAS Number
4205-91-8
Molecular Formula
C9H9Cl2N3 • HCl
Formula Weight
266.6
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMSO: 3 mg/mlEthanol: 3 mg/mlPBS (pH 7.2): 3 mg/ml
SMILES
ClC1=C(NC2=NCCN2)C(Cl)=CC=C1.Cl
InChi Code
InChI=1S/C9H9Cl2N3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-3H,4-5H2,(H2,12,13,14);1H
InChi Key
ZNIFSRGNXRYGHF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Clonidine (hydrochloride) (Item No. 38558) is an analytical reference standard categorized as an α2-adrenergic receptor agonist.1 Formulations containing clonidine have been used in the treatment of opioid withdrawal.2 This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 15949).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jasper, J.R., Lesnick, J.D., Chang, L.K., et al. Ligand efficacy and potency at recombinant α2 adrenergic receptors: Agonist-mediated [35S]GTPγS binding. Biochem. Pharmacol. 55(7), 1035-1043 (1998).

    2. Kuszmaul, A.K., Palmer, E.C., and Frederick, E.K. Lofexidine versus clonidine for mitigation of opioid withdrawal symptoms: A systematic review. J. Am. Pharm. Assoc. (2003) 60(1), 145-152 (2020).