A derivative of NAD+
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N6-(2-aminoethyl)-NAD+

Item No. 38569

Technical Information
Formal Name
N-(2-aminoethyl)-adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt, monosodium salt
Synonyms
  • N6-(2-aminoethyl)-Nicotinamide adenine dinucleotide
Molecular Formula
C23H31N8O14P2 • Na
Formula Weight
Purity
≥95%
A solid
Water: Soluble
SMILES
O[C@@H]1[C@H](O)[C@@H](COP([O-])(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H]([N+]3=CC(C(N)=O)=CC=C3)O2)([O-])=O)=O)O[C@H]1N4C=NC5=C(NCCN)N=CN=C54.[Na+]
InChi Code
InChI=1S/C23H32N8O14P2.Na/c24-3-4-26-20-14-21(28-9-27-20)31(10-29-14)23-18(35)16(33)13(44-23)8-42-47(39,40)45-46(37,38)41-7-12-15(32)17(34)22(43-12)30-5-1-2-11(6-30)19(25)36;/h1-2,5-6,9-10,12-13,15-18,22-23,32-35H,3-4,7-8,24H2,(H4-,25,26,27,28,36,37,38,39,40);/q;+1/p-1/t12-,13-,15-,16-,17-,18-,22-,23-;/m1./s1
InChi Key
UWIPQVIWBYYMIT-JIVSRYSWSA-M
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    Product Description

    N6-(2-aminoethyl)-NAD+ is a derivative of the signaling molecule and enzyme cofactor NAD+ (Item No. 16077).1 It has been conjugated to various matrices, including sepharose and dextran, for affinity chromatography of NAD+-dependent enzymes. N6-(2-aminoethyl)-NAD+ has also been conjugated to silylated chips via pyrroloquinoline quinone (PQQ; Item No. 20681) to act as a biosensor for lactate.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Schmidt, H.-L., and Grenner, G. Coenzyme properties of NAD+ bound to different matrices through the amino group in the 6-position. Eur. J. Biochem. 67(1), 295-302 (1976).

    2. Zayats, M., Kharitonov, A.B., Katz, E., et alAn integrated NAD+-dependent enzyme-functionalized field-effect transistor (ENFET) system: Development of a lactate biosensor. Biosens. Bioelectron. 15(11-12), 671-680 (2000).