An ionizable cationic lipidoid
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304O13

Item No. 38584

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N,N′,N′′-(nitrilotri-2,1-ethanediyl)tris[N-methyl-β-alanine, 1,1′,1′′- tritridecyl ester
CAS Number
1566559-80-5
Molecular Formula
C57H114N4O6
Formula Weight
951.5
Purity
≥95%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Ethanol: Soluble
SMILES
O=C(OCCCCCCCCCCCCC)CCN(C)CCN(CCN(C)CCC(OCCCCCCCCCCCCC)=O)CCN(C)CCC(OCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C57H114N4O6/c1-7-10-13-16-19-22-25-28-31-34-37-52-65-55(62)40-43-58(4)46-49-61(50-47-59(5)44-41-56(63)66-53-38-35-32-29-26-23-20-17-14-11-8-2)51-48-60(6)45-42-57(64)67-54-39-36-33-30-27-24-21-18-15-12-9-3/h7-54H2,1-6H3
InChi Key
FXFXNAQYPHPPBV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $48

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    5 mg

    $228

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    10 mg

    $384

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    25 mg

    $900

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    Cayman Chemical
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    Product Description

    304O13 is an ionizable cationic lipidoid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vivo.1 LNPs containing 304O13 and encapsulating siRNA targeting Factor VII mRNA decrease serum Factor VII levels in mice.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Whitehead , K.A., Dorkin, J.R., Vegas, A.J., et al. Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity. Nat. Commun. 5, 4277 (2014).