An enantiomer of 13(S)-HODE
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Enantiomer(s)
3861013(S)-HODE
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13(R)-HODE

Item No. 38605

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
13R-hydroxy-9Z,11E-octadecadienoic acid
CAS Number
10219-69-9
Molecular Formula
C18H32O3
Formula Weight
296.5
Purity
≥98%
Formulation (Request formulation change)
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/mlPBS pH 7.2: 1 mg/ml
λmax
234 nm
SMILES
CCCCC[C@@H](O)\C=C\C=C\CCCCCCCC(=O)O
InChi Code
InChI=1S/C18H32O3/c1-2-3-11-14-17(19)15-12-9-7-5-4-6-8-10-13-16-18(20)21/h7,9,12,15,17,19H,2-6,8,10-11,13-14,16H2,1H3,(H,20,21)/b9-7-,15-12+/t17-/m1/s1
InChi Key
HNICUWMFWZBIFP-PIHGWCCBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    25 µg

    $90

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    50 µg

    $151

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    100 µg

    $262

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    250 µg

    $609

    Add
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    Product Description

    13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.1 13(R)-HODE is a weak (IC50 = 2.7 µM) inhibitor of U-46619-induced platelet aggregation.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baer, A.N., Costello, P.B., and Green, F.A. Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells. Biochim. Biophys. Acta 1085(1), 45-52 (1991).

    2. Lagarde, M., Boutillon, M.M., Guichardant, M., et al. Further studies on the anti-thromboxane A2 activity of monohydroxylated fatty acids. Biochem. Pharmacol. 38, 1863-1864 (1989).