A mixture of GTP derivatives
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2'(3')-O-(6-Aminohexylcarbamoyl)guanosine-5'-O-triphosphate (sodium salt)

Item No. 38659

Technical Information
Formal Name
guanosine 5'-(tetrahydrogen triphosphate), 2'(or 3')-[N-(6-aminohexyl)carbamate], tetrasodium salt
Synonyms
  • 2'(3')-AHC-GTP
Molecular Formula
C17H26N7O15P3 • 4Na
Formula Weight
Purity
≥95% (mixture of isomers)
A solution in water
Water: Soluble
SMILES
O=C(NCCCCCCN)O[C@H]([C@@H]1O)[C@H](N2C(NC(N)=NC3=O)=C3N=C2)O[C@@H]1CO[P](O[P](OP([O-])([O-])=O)([O-])=O)([O-])=O.O[C@H]([C@@H]4OC(NCCCCCCN)=O)[C@H](N5C(NC(N)=NC6=O)=C6N=C5)O[C@@H]4CO[P](O[P](OP([O-])([O-])=O)([O-])=O)([O-])=O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/2C17H30N7O15P3.8Na/c18-5-3-1-2-4-6-20-17(27)37-12-9(7-35-41(31,32)39-42(33,34)38-40(28,29)30)36-15(11(12)25)24-8-21-10-13(24)22-16(19)23-14(10)26;18-5-3-1-2-4-6-20-17(27)37-12-11(25)9(7-35-41(31,32)39-42(33,34)38-40(28,29)30)36-15(12)24-8-21-10-13(24)22-16(19)23-14(10)26;;;;;;;;/h2*8-9,11-12,15,25H,1-7,18H2,(H,20,27)(H,31,32)(H,33,34)(H2,28,29,30)(H3,19,22,23,26);;;;;;;;/q;;8*+1/p-8/t2*9-,11-,12-,15-;;;;;;;;/m11......../s1
InChi Key
OUACOKGVRKTZAN-RZIDVFHFSA-F
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    2'(3')-O-(6-Aminohexylcarbamoyl)guanosine-5'-O-triphosphate (2'(3')-AHC-GTP) is a mixture of the energy substrate for protein synthesis and gluconeogenesis guanosine 5′-triphosphate (GTP; Item No. 16060) derivatives 2'-AHC-GTP and 3'-AHC-GTP. 2'(3')-AHC-GTP has been used in the synthesis of europium (III) chelates for use in quenching resonance energy transfer (QRET) assays in the study of GTPase nucleotide exchange kinetics.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kopra, K., Ligabue, A., Wang, Q., et al. A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction. Anal. Bioanal. Chem. 406(17), 4147-4156 (2014).