A methylated derivative of GTP
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3'-O-Methylguanosine-5'-O-triphosphate (sodium salt)

Item No. 38688

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3′-O-methyl-guanosine 5′-(tetrahydrogen triphosphate), tetrasodium salt
CAS Number
98923-57-0
Synonyms
  • 3'-O-methyl GTP
Molecular Formula
C11H14N5O14P3 • 4Na
Formula Weight
625.1
Purity
≥95%
Formulation (Request formulation change)
A solution in water
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
[O-]P([O-])(OP([O-])(OP([O-])(OC[C@H]1O[C@@H](N2C=NC3=C2NC(N)=NC3=O)[C@H](O)[C@@H]1OC)=O)=O)=O.[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C11H18N5O14P3.4Na/c1-26-7-4(2-27-32(22,23)30-33(24,25)29-31(19,20)21)28-10(6(7)17)16-3-13-5-8(16)14-11(12)15-9(5)18;;;;/h3-4,6-7,10,17H,2H2,1H3,(H,22,23)(H,24,25)(H2,19,20,21)(H3,12,14,15,18);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1
InChi Key
ONIAXFLJUIIDFW-KWIZKVQNSA-J
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    2.7 mg

    $355

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    Product Description

    3'-O-Methylguanosine-5'-O-triphosphate (3'-O-methyl GTP) is a methylated derivative of GTP (Item No. 16060).1 It has been used as a chain termination reagent in the preparation of early RNA polymerase II elongation intermediates.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Dvir, A., Conaway, J.W., and Conaway, R.C. Assays for investigating the mechanism of promoter escape by RNA polymerase II. Methods Enzymol. 370, 733-740 (2003).