An ionizable cationic lipid
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Isomer(s)
34372Lipid 5 33474SM-102
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Lipid M

Item No. 38775

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-octyl-decanoic acid, 7-[(2-hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]heptyl ester
CAS Number
2089251-57-8
Molecular Formula
C44H87NO5
Formula Weight
710.2
Purity
≥95%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly Soluble: 0.1-1 mg/mlEthanol: Sparingly Soluble: 1-10 mg/mlMethanol: Sparingly Soluble: 1-10 mg/ml
SMILES
O=C(CCCCCCCN(CCCCCCCOC(C(CCCCCCCC)CCCCCCCC)=O)CCO)OCCCCCCCCC
InChi Code
InChI=1S/C44H87NO5/c1-4-7-10-13-16-24-31-40-49-43(47)35-28-21-17-22-29-36-45(38-39-46)37-30-23-18-25-32-41-50-44(48)42(33-26-19-14-11-8-5-2)34-27-20-15-12-9-6-3/h42,46H,4-41H2,1-3H3
InChi Key
QNTJORIUGGAOBT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $102

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    5 mg

    $329

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    Cayman Chemical
    Ionizable Lipids – Your Path from R&D to GMP

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    Product Description

    Lipid M is an ionizable cationic lipid (pKa = 6.75) that has been used in the generation of lipid nanoparticles (LNPs) for mRNA delivery in vivo.1 LNPs containing lipid M and encapsulating mRNA encoding influenza virus genes increase anti-influenza virus IgG titers in cynomolgus monkeys without inducing local edema, erythema, or systemic levels of IL-6.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hassett, K.J., Benenato, K.E., Jacquinet, E., et al. Optimization of lipid nanoparticles for intramuscular administration of mRNA vaccines. Mol. Ther. Nucleic Acids 15, 1-11 (2019).