A TLR7 agonist
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LHC165 (hydrate)

Item No. 38776

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]-benzo[f][1,7]naphthyridine-8-propanoic acid, hydrate
Molecular Formula
C29H32F2N3O7P • XH2O
Formula Weight
603.6
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: 30 mg/ml
λmax
233 nm
SMILES
NC1=C(N=C2)C(C=C2CCC(C=CC(OCCOCCC(F)(F)[P](O)(O)=O)=C3)=C3C)=C(C=CC(CCC(O)=O)=C4)C4=N1.O
InChi Code
InChI=1S/C29H32F2N3O7P.H2O/c1-18-14-22(41-13-12-40-11-10-29(30,31)42(37,38)39)7-6-21(18)5-2-20-15-24-23-8-3-19(4-9-26(35)36)16-25(23)34-28(32)27(24)33-17-20;/h3,6-8,14-17H,2,4-5,9-13H2,1H3,(H2,32,34)(H,35,36)(H2,37,38,39);1H2
InChi Key
AIYLPQQMABCVIZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $105

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    5 mg

    $340

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    Cayman Chemical
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    Product Description

    LHC165 is a toll-like receptor 7 (TLR7) agonist.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zawit, M., Swami, U., Awada, H., et al. Current status of intralesional agents in treatment of malignant melanoma. Ann. Transl. Med. 9(12), 1038 (2021).