GTP derivatives
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2'(3')-O-(5-Bromoanthraniloyl)guanosine-5'-O-triphosphate (sodium salt)

Item No. 38816

Technical Information
Formal Name
2′(or 3′)-(2-amino-5-bromobenzoate) guanosine 5′-(tetrahydrogen triphosphate), tetrasodium salt
Synonyms
  • 2'(3')-bromo ANT-GTP
Molecular Formula
C17H16BrN6O15P3 • 4Na
Formula Weight
Purity
≥95% (mixture of isomers)
Emission
426 nm
Excitation
346 nm
A solution in water
Water: Soluble
SMILES
O=C1N=C(N)NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OC(C4=C(N)C=CC(Br)=C4)=O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O3.O[C@@H]5[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@@H](N6C(NC(N)=NC7=O)=C7N=C6)[C@@H]5OC(C8=C(N)C=CC(Br)=C8)=O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/2C17H20BrN6O15P3.8Na/c18-6-1-2-8(19)7(3-6)16(27)37-12-9(4-35-41(31,32)39-42(33,34)38-40(28,29)30)36-15(11(12)25)24-5-21-10-13(24)22-17(20)23-14(10)26;18-6-1-2-8(19)7(3-6)16(27)37-12-11(25)9(4-35-41(31,32)39-42(33,34)38-40(28,29)30)36-15(12)24-5-21-10-13(24)22-17(20)23-14(10)26;;;;;;;;/h2*1-3,5,9,11-12,15,25H,4,19H2,(H,31,32)(H,33,34)(H2,28,29,30)(H3,20,22,23,26);;;;;;;;/q;;8*+1/p-8/t2*9-,11-,12-,15-;;;;;;;;/m11......../s1
InChi Key
OZHLMZFESSFRSN-RZIDVFHFSA-F
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    2'-O-(5-Bromoanthraniloyl)guanosine-5'-O-triphosphate (2'-bromo ANT-GTP) and 3'-bromo ANT-GTP are derivatives of GTP, that may undergo spontaneous isomerization.1 2'(3')-bromo ANT-GTP displays excitation/emission maxima of 346/426 nm, respectively.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Geduhn, J., Dove, S., Shen, Y., et alBis-halogen-anthraniloyl-substituted nucleoside 5'-triphosphates as potent and selective inhibitors of Bordetella pertussis adenylyl cyclase toxin. J. Pharmacol. Exp. Ther. 336(1), 104-115 (2011).