A peptide fragment of β-casein
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KEMPFPKYPVEP Peptide (bovine, ovine) (trifluoroacetate salt)

Item No. 38850

Technical Information
Formal Name
L-lysyl-L-α-glutamyl-L-methionyl-L-prolyl-L-phenylalanyl-L-prolyl-L-lysyl-L-tyrosyl-L-prolyl-L-valyl-L-α-glutamyl-L-proline, trifluoroacetate salt
Molecular Formula
C70H104N14O18S • XCF3COOH
Formula Weight
Purity
≥95%
A solid
Peptide Sequence
KEMPFPKYPVEP-OH
Water: Soluble
SMILES
[H]N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N2CCC[C@H]2C(N[C@@H](CCCCN)C(N[C@H](C(N3CCC[C@H]3C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N4CCC[C@H]4C(O)=O)=O)=O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)CC6=CC=CC=C6)=O)=O)CCSC)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C70H104N14O18S.C2HF3O2/c1-41(2)58(65(96)77-48(28-30-57(88)89)66(97)84-37-14-22-55(84)70(101)102)80-64(95)54-21-13-36-83(54)68(99)50(40-43-23-25-44(85)26-24-43)78-60(91)46(18-8-10-33-72)75-62(93)52-19-12-35-82(52)69(100)51(39-42-15-5-4-6-16-42)79-63(94)53-20-11-34-81(53)67(98)49(31-38-103-3)76-61(92)47(27-29-56(86)87)74-59(90)45(73)17-7-9-32-71;3-2(4,5)1(6)7/h4-6,15-16,23-26,41,45-55,58,85H,7-14,17-22,27-40,71-73H2,1-3H3,(H,74,90)(H,75,93)(H,76,92)(H,77,96)(H,78,91)(H,79,94)(H,80,95)(H,86,87)(H,88,89)(H,101,102);(H,6,7)/t45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,58-;/m0./s1
InChi Key
JRKRHSHNMJBSSW-BWYZSTATSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    KEMPFPKYPVEP Peptide is a peptide fragment of the dairy protein β-casein.1,2 It can be produced by the protease M from A. oryzae and is found in dairy products fermented by fungi but not bacteria.1 KEMPFPKYPVEP Peptide (2 mg/kg) increases the levels of dopamine, norepinephrine, and homovanillic acid, but not serotonin, in the frontal cortex of mice. It improves spatial alternation retention in the Y-maze spatial alternation task and increases novel object exploration time in a novel object recognition test in a mouse model of scopolamine-induced amnesia when administered at a dose of 2 mg/kg.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ano, Y., Kutsukake, T., Sasaki, T., et alIdentification of a novel peptide from β-casein that enhances spatial and object recognition memory in mice. J. Agric. Food Chem. 67(29), 8160-8167 (2019).

    2. Atamer, Z., Post, A.E., Schubert, T., et alBovine β-casein: Isolation, properties and functionality. A review. Int. Dairy J. 66, 115-125 (2017).