A cationic lipid
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Dimethyldimyristylammonium (bromide)

Item No. 38870

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N,N-dimethyl-N-tetradecyl-1-tetradecanaminium, monobromide
CAS Number
68105-02-2
Synonyms
  • Dimethylditetradecylammonium
Molecular Formula
C30H64N • Br
Formula Weight
518.7
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): Slightly soluble
SMILES
CCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCC.[Br-]
InChi Code
InChI=1S/C30H64N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31(3,4)30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-30H2,1-4H3;1H/q+1;/p-1
InChi Key
IRMGVPILCPGYNQ-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Dimethyldimyristylammonium is a cationic lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs).1 Administration of LNPs containing dimethyldimyristylammonium and encapsulating mRNA encoding a luciferase reporter increase luminescence in HeLa cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tang, M., Sagawa, A., Inoue, N., et al. Efficient mRNA delivery with mRNA lipoplexes prepared using a modified ethanol injection method. Pharmaceutics 15(4), 1141 (2023).