A thiol-reactive fluorogenic reagent
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ABD-F

Item No. 38892

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7-fluoro-2,1,3-benzoxadiazole-4-sulfonamide
CAS Number
91366-65-3
Molecular Formula
C6H4FN3O3S
Formula Weight
217.2
Purity
≥98%
Emission
513 nm
Excitation
389 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): Slightly
SMILES
O=S(N)(C1=CC=C(C2=NON=C21)F)=O
InChi Code
InChI=1S/C6H4FN3O3S/c7-3-1-2-4(14(8,11)12)6-5(3)9-13-10-6/h1-2H,(H2,8,11,12)
InChi Key
XROXHZMRDABMHS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $44

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    10 mg

    $84

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    25 mg

    $176

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    50 mg

    $329

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    Product Description

    ABD-F is a thiol-reactive fluorogenic reagent.1 It has been used to detect and quantify thiol-containing amino acids, protein and tissue thiols, and disulfide bridges between proteins.1,2,3 ABD-F displays excitation/emission maxima of 389 and 513 nm, respectively.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Toyo’oka, T., and Imai, K. New fluorogenic reagent having halogenobenzofurazan structure for thiols: 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole. Anal. Chem. 56(13), 2461-2464 (1984).

    2. Takeda, M., Makita, H., Ohno, K., et al. Structural analysis of the sheath of a sheathed bacterium, Leptothrix cholodnii. Int. J. Biol. Macromol. 37(1-2), 92-98 (2005).

    3. Toyo'oka, T., Furukawa, F., Suzuki, T., et al. Determination of thiols and disulfides in normal rat tissues and hamster pancreas treated with N-nitrosobis(2-oxopropyl)amine using 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and ammonium 7-fluoro-2,1,3-benzoxadiazole-4-sulfonate. Biomed. Chromatogr. 3(4), 166-172 (1989).