A fluorenone and DPP-3 inhibitor
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Fluostatin A (sodium salt)

Item No. 38913

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6,7-dihydroxy-3-methyl-1H-benzo[a]fluorene-1,4,11-trione, monosodium salt
CAS Number
209673-93-8
Molecular Formula
C18H9O5 • Na
Formula Weight
328.3
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleWater: Soluble
SMILES
O=C1C=C(C)C(C2=C1C(C(C3=C4C(O)=CC=C3)=O)=C4C([O-])=C2)=O.[Na+]
InChi Code
InChI=1S/C18H10O5.Na/c1-7-5-11(20)14-9(17(7)22)6-12(21)15-13-8(18(23)16(14)15)3-2-4-10(13)19;/h2-6,19,21H,1H3;/q;+1/p-1
InChi Key
ORZHCFYIRAXBFY-UHFFFAOYSA-M
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $534

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    Product Description

    Fluostatin A is a fluorenone originally isolated from Streptomyces.1 It selectively inhibits dipeptidyl peptidase 3 (DPP-3) over DPP-1, DPP-2, and DPP-4 (IC50s = 0.44, >100, >100, and >100 µg/ml, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Akiyama, T., Harada, S., Kojima, F., et al. Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. I. Taxonomy of producing strain, production, isolation, physico-chemical properties and biological properties. J. Antibiot. (Tokyo) 51(6), 553-559 (1998).