An oligosaccharide
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Lacto-N-tetraose

Item No. 39034

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-D-glucose
CAS Number
14116-68-8
Synonyms
  • LNT
Molecular Formula
C26H45NO21
Formula Weight
707.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
CC(N[C@H]([C@H]([C@@H]1O)O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@@H]2O)CO)[C@@H](O[C@@H]1CO)O[C@@H]([C@H]([C@H]3CO)O)[C@H]([C@@H](O3)O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O)=O
InChi Code
InChI=1S/C26H45NO21/c1-7(33)27-13-22(47-25-19(41)18(40)15(37)10(4-30)44-25)16(38)11(5-31)43-24(13)48-23-17(39)12(6-32)45-26(20(23)42)46-21(9(35)3-29)14(36)8(34)2-28/h2,8-26,29-32,34-42H,3-6H2,1H3,(H,27,33)/t8-,9+,10+,11+,12+,13+,14+,15-,16+,17-,18-,19+,20+,21+,22+,23-,24-,25-,26-/m0/s1
InChi Key
USIPEGYTBGEPJN-TYWGMFGMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Cayman Chemical
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    Product Description

    Lacto-N-tetraose (LNT) is an oligosaccharide that has been found in human breast milk.1 It is fermented by gut microbiota and promotes the growth of the bacterium B. longum and B. breve. Levels of LNT are increased in breast milk from mothers of rotavirus-positive neonates with gastrointestinal symptoms and are positively correlated with levels of Enterobacter and Klebsiella in maternal milk and infant stool.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hu, M., Miao, M., Li, K., et al. Human milk oligosaccharide lacto-N-tetraose: Physiological functions and synthesis methods. Carbohydr. Polym. 316:121067, (2023).

    2. Ramani, S., Stewart, C.J., Laucirica, D.R., et al. Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection. Nat. Commun. 9(1), 5010 (2018).