An azide-containing form of polysarcosine150
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Azide-Polysarcosine150

Item No. 39041

Technical Information
Formal Name
N-(3-azidopropyl)-2-(methyl((methylamino)methyl)amino)acetamide
Synonyms
  • Azide-pSar150
  • N3-pSar150
  • N3-Polysarcosine150
Molecular Formula
(C3H5NO)nC5H13N5
Purity
≥90%
A solid
Chloroform: Soluble
SMILES
O=C(CN(C)CNC)NCCCN=[N+]=[N-]
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Azide-polysarcosine150 is an azide-containing form of the amine-functionalized hydrophilic polymer polysarcosine150 (Item No. 39051).1 Azide-polysarcosines have been used in the formation of hydrophobicity-masking antibody-drug conjugates for the selective release of monomethyl auristatin E (Item No. 16267) to tumors in rats.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Viricel, W., Fournet, G., Beaumel, S., et alMonodisperse polysarcosine-based highly-loaded antibody-drug conjugates. Chem. Sci. 10(14), 4048-4053 (2019).