A hydroxyl-terminated PAMAM dendrimer
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PAMAM Dendrimer G6.0 Amidoethanol (water solution)

Item No. 39115

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • PAMAM 6.0 Amidoethanol
  • Polyamidoamine Dendrimer G6.0 Amidoethanol
Molecular Formula
[NH2(CH2)2NH2]:(G=6);dendri PAMAM(NHCH2CH2OH)256
Formula Weight
58298.2
Formulation (Request formulation change)
A solution in water
Solubility(Learn about Variance in Solubility)
Water: soluble
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    50 mg

    $87

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    100 mg

    $165

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    Product Description

    PAMAM dendrimer G6.0 amidoethanol (PAMAM G6.0-OH) is a polyamidoamine (PAMAM) dendrimer with hydroxyl termini. It is approximately 65 Å in diameter in PBS.1 PAMAM G6.0-OH induces mortality in zebrafish embryos to a lesser extent than PAMAM dendrimer G6.0 amine (Item No. 39076) but to a greater extent than PAMAM dendrimer G6.0 succinamic acid (Item No. 39123) when used at a concentration of 250 ppm in the tank water.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Dobrovolskaia, M.A., Patri, A.K., Simak, J., et al. Nanoparticle size and surface charge determine effects of PAMAM dendrimers on human platelets in vitro. Mol. Pharm. 9(3), 382-393 (2012).

    2. Pryor, J.B., Harper, B.J., and Harper, S.L. Comparative toxicological assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish. Int. J. Nanomedicine 9, 1947-1956 (2014).