Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Visit our FAQ
Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888
Item No. 39125
Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.
Collagen type II (358-368)-biotin peptide is a biotinylated version of the fibril-forming heterotrimeric protein collagen type II, which undergoes citrullination by peptidyl arginine deiminase 2 (PAD2) and PAD4.1 Citrullinated collagen type II (358-368) has been found in synovial fluid isolated from patients with rheumatoid arthritis.2,1 Cayman’s Collagen Type II (358-368)-biotin Peptide is intended for use as a negative control in the detection of autoantibodies against citrullinated collagen and is the non-citrullinated form of Citrullinated Collagen Type II (R360+R365) (358-368)-biotin Peptide (Item No. 39126).
WARNING This product is not for human or veterinary use.
1. Peptidyl arginine deiminase type 2 (PAD-
2. Antibodies to citrullinated proteins: Molecular interactions and arthritogenicity. Immunol. Rev. 233(1), 9-33 (2009).