A biotinylated collagen peptide
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Collagen Type II (358-368)-biotin Peptide

Item No. 39125

Technical Information
Synonyms
  • Biotin-Gly-Ala-Arg-Gly-Leu-Thr-Gly-Arg-Pro-Gly-Asp-Ala
Formula Weight
1353.5
Purity
≥95%
A solid
Peptide Sequence
Biotin-GARGLTGRPGDA
UniProt Accession №
P02458
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    Collagen type II (358-368)-biotin peptide is a biotinylated version of the fibril-forming heterotrimeric protein collagen type II, which undergoes citrullination by peptidyl arginine deiminase 2 (PAD2) and PAD4.1 Citrullinated collagen type II (358-368) has been found in synovial fluid isolated from patients with rheumatoid arthritis.2,1 Cayman’s Collagen Type II (358-368)-biotin Peptide is intended for use as a negative control in the detection of autoantibodies against citrullinated collagen and is the non-citrullinated form of Citrullinated Collagen Type II (R360+R365) (358-368)-biotin Peptide (Item No. 39126).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Foulquier, C., Sebbag, M., Clavel, C., et alPeptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation. Arthritis Rheum. 56(11), 3541-3553 (2007).

    2. Uysal, H., Nandakumar, K.S., Kessel, C., et alAntibodies to citrullinated proteins: Molecular interactions and arthritogenicity. Immunol. Rev. 233(1), 9-33 (2009).