An apoptosis inducer
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Raptinal

Item No. 39131

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
[9,9′-Bi-9H-fluorene]-9,9′-dicarboxaldehyde
CAS Number
1176-09-6
Synonyms
  • 9H,9′H-9,9′-Bifluorene-9,9′-dicarbaldehyde
  • NSC 610970
  • SML1745
Molecular Formula
C28H18O2
Formula Weight
386.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly soluble: 0.1-1 mg/mlEthanol: Slightly soluble: 0.1-1 mg/mlPBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml
SMILES
O=CC1(C2(C3=C(C4=C2C=CC=C4)C=CC=C3)C=O)C5=C(C6=C1C=CC=C6)C=CC=C5
InChi Code
InChI=1S/C28H18O2/c29-17-27(23-13-5-1-9-19(23)20-10-2-6-14-24(20)27)28(18-30)25-15-7-3-11-21(25)22-12-4-8-16-26(22)28/h1-18H
InChi Key
GLANOOJJBKXTMI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $28

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    5 mg

    $104

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    10 mg

    $165

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    25 mg

    $241

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    Cayman Chemical
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    Product Description

    Raptinal is an inducer of apoptosis.1 It is hydrolyzed into its active form in aqueous solutions. Raptinal (10 µM) induces apoptosis in 17 cancerous and HFF-1 IRR, MCF-10A, MEFs, and 3T3-SA non-cancerous cells. In vivo, raptinal (20 mg/kg per day) decreases tumor mass in a 4T1 murine breast cancer model.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Palchaudhuri, R., Lambrecht, M.J., Botham, R.C., et al. A small molecule that induces intrinsic pathway apoptosis with unparalleled speed. Cell Rep. 13(9), 2027-2036 (2015).