A muscle relaxant
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Product Type

Chlorphenesin Carbamate

Item No. 39252

Technical Information
Formal Name
3-(4-chlorophenoxy)-1,2-propanediol, 1-carbamate
CAS Number
886-74-8
Synonyms
  • Maolate
  • NSC 82943
  • OC-201
Molecular Formula
C10H12ClNO4
Formula Weight
Purity
≥98%
A solid
Methanol: Soluble
SMILES
O=C(N)OCC(COC1=CC=C(C=C1)Cl)O
InChi Code
InChI=1S/C10H12ClNO4/c11-7-1-3-9(4-2-7)15-5-8(13)6-16-10(12)14/h1-4,8,13H,5-6H2,(H2,12,14)
InChi Key
SKPLBLUECSEIFO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Chlorphenesin carbamate is a muscle relaxant.1 It decreases the dorsal root potential induced by a current-stimulated ventral root, as well as L-glutamate-induced motor neuron discharges, in isolated frog spinal cords when used at a concentration of 1 mM. In vivo, chlorphenesin carbamate (50 mg/kg) reduces the amplitude of polysynaptic responses in ipsilateral ventral root L5 induced by electrical stimulation of dorsal root L5 in spinalized rats.2 It decreases monosynaptic signal transfer from primary afferent fibers to motor neurons in the same animals at the same dose. Formulations containing chlorphenesin carbamate have been used in the treatment of post-surgical pain, acute inflammation, and as a muscle relaxant in veterinary applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aihara, H., Kurachi, M., Nakane, S., et alThe action of chlorphenesin carbamate on the frog spinal cord. Jpn. J. Pharmacol. 30(1), 29-36 (1980).

    2. Kurachi, M., and Aihara, H. Effect of a muscle relaxant, chlorphenesin carbamate, on the spinal neurons of rats. Jpn. J. Pharmacol. 36(1), 7-13 (1984).