An ionizable cationic lipidoid
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C12-113

Item No. 39335

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,1′,1′′,1′′′-[(methylimino)bis(2,1-ethanediylnitrilo)]tetrakis-2-dodecanol
CAS Number
1220890-27-6
Molecular Formula
C53H111N3O4
Formula Weight
854.5
Purity
≥95%
Formulation (Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
DMSO: 20 mg/mlEthanol: 25 mg/ml
SMILES
OC(CCCCCCCCCC)CN(CCN(CCN(CC(CCCCCCCCCC)O)CC(O)CCCCCCCCCC)C)CC(O)CCCCCCCCCC
InChi Code
InChI=1S/C53H111N3O4/c1-6-10-14-18-22-26-30-34-38-50(57)46-55(47-51(58)39-35-31-27-23-19-15-11-7-2)44-42-54(5)43-45-56(48-52(59)40-36-32-28-24-20-16-12-8-3)49-53(60)41-37-33-29-25-21-17-13-9-4/h50-53,57-60H,6-49H2,1-5H3
InChi Key
LVXMNISFCHVOGG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $112

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    10 mg

    $201

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    25 mg

    $445

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    Product Description

    C12-113 is an ionizable cationic lipidoid.1 It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA encoding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein in mice.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Han, X., Alameh, M.-G., Butowska, K., et al. Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines. Nat. Nanotechnol. (2023).