An Analytical Reference Standard
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Alternative(s)
10011133Papaverine
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Papaverine (hydrochloride)

Item No. 39361

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline, monohydrochloride
CAS Number
61-25-6
Molecular Formula
C20H21NO4 • HCl
Formula Weight
375.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 10 mg/mlEthanol: 1 mg/mlPBS (pH 7.2): Slightly soluble
λmax
253 nm
SMILES
COC1=C(OC)C=C(C=CN=C2CC3=CC(OC)=C(OC)C=C3)C2=C1.Cl
InChi Code
InChI=1S/C20H21NO4.ClH/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16;/h5-8,10-12H,9H2,1-4H3;1H
InChi Key
UOTMYNBWXDUBNX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Papaverine (Item No. 39361) is an analytical reference standard categorized as a muscle relaxant.1,2,3 Papaverine has been found as an impurity in seized heroin.4 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Virag, R., Shoukry, K., Floresco, J., et al. Intracavernous self-injection of vasoactive drugs in the treatment of impotence: 8-Year experience with 615 cases. J. Urol. 145(2), 287-293 (1991).

    2. Vardiman, A.B., Kopitnik, T.A., Purdy, P.D., et al. Treatment of traumatic arterial vasospasm with intraarterial papaverine infusion. AJNR Am. J. Neuroradiol. 16(2), 319-321 (1995).

    3. Triner, L., Vulliemoz, Y., Schwartz, I., et al. Cyclic phosphodiesterase activity and the action of papaverine. Biochem. Biophys. Res. Commun. 40(1), 64-69 (1970).

    4. Cui, X., Lian, R., Chen, J., et al. Source identification of heroin by rapid detection of organic impurities using direct analysis in real time with high-resolution mass spectrometry and multivariate statistical analysis. Microchem. J. 147, 121-126 (2019).