A pteridine with antibacterial activity
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Product Categories

Product Type

Biochemicals
Antibiotics
Natural Products

Research Area

Cancer
Infectious Disease
Bacterial Diseases

Application

Pterin

Item No. 39503

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-amino-4(3H)-pteridinone
CAS Number
2236-60-4
Synonyms
  • NSC 11540
  • NSC 18696
  • NSC 170929
Molecular Formula
C6H5N5O
Formula Weight
163.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: SolubleWater: Soluble
SMILES
O=C1N=C(N)N=C2NC=CN=C12
InChi Code
InChI=1S/C6H5N5O/c7-6-10-4-3(5(12)11-6)8-1-2-9-4/h1-2H,(H3,7,9,10,11,12)
InChi Key
HNXQXTQTPAJEJL-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $39

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    100 mg

    $62

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    250 mg

    $97

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    500 mg

    $174

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    Cayman Chemical
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    Product Description

    Pterin is a pteridine that has been found in C. croceus and has antibacterial activity.1,2 It reduces the proliferation of, and biofilm production by, E. coli, P. aeruginosa, and S. mutans when used at concentrations of 100 or 150 µg/ml.2 Pterin levels are increased in urine samples from patients with breast, lung, colon, or rectal cancer.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Descimon, H. Pterins of Pieridae (Lepidoptera) and their biosynthesis. I. Identification of the main pterins of Colias croceus (Fourcroy) and of some other species of Pieridae. Biochimie 53(3), 407-418 (1971).

    2. Mahendran, R., Thandeeswaran, M., Kiran, G., et al. Evaluation of pterin, a promising drug candidate from cyanide degrading bacteria. Curr. Microbiol. 75(6), 684-693 (2018).

    3. Gamagedara, S., Gibbons, S., and Ma, Y. Investigation of urinary pteridine levels as potential biomarkers for noninvasive diagnosis of cancer. Clin. Chim. Acta. 412(1-2), 120-128 (2011).