A saturated acyl CoA
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Myristoyl-Coenzyme A (imidazole salt)

Item No. 39777

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
S-tetradecanoate coenzyme A, tri-imidazole salt
Synonyms
  • Myristoyl-CoA
  • Tetradecanoyl-CoA
Molecular Formula
C35H62N7O17P3S • 3C3H4N2
Formula Weight
1182.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 10 mg/ml
SMILES
O[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCCCCCCCCCCCC)=O)=O)=O)(O)=O)(O)=O)[C@H]1OP(O)(O)=O.C4=CN=CN4.C5=CN=CN5.C6=CN=CN6
InChi Code
InChI=1S/C35H62N7O17P3S.3C3H4N2/c1-4-5-6-7-8-9-10-11-12-13-14-15-26(44)63-19-18-37-25(43)16-17-38-33(47)30(46)35(2,3)21-56-62(53,54)59-61(51,52)55-20-24-29(58-60(48,49)50)28(45)34(57-24)42-23-41-27-31(36)39-22-40-32(27)42;3*1-2-5-3-4-1/h22-24,28-30,34,45-46H,4-21H2,1-3H3,(H,37,43)(H,38,47)(H,51,52)(H,53,54)(H2,36,39,40)(H2,48,49,50);3*1-3H,(H,4,5)/t24-,28-,29-,30+,34-;;;/m1.../s1
InChi Key
DOCJLHKQDKYXCM-HWJSJFDLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    5 mg

    $197

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    10 mg

    $335

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    25 mg

    $640

    Add
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    Product Description

    Myristoyl-coenzyme A (myristoyl-CoA) is a derivative of CoA (Item No. 16147) that contains the saturated fatty acid myristic acid (Item No. 13351). It is a substrate for N-myristoyltransferase during myristoylation, a process that adds a myristoyl group to proteins either during translation to modify protein activity or post-translationally in apoptotic cells.1,2 It is also a substrate in the de novo synthesis of phosphatidylinositol.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bhatnagar, R.S., Fütterer, K., Waksman, G., et al. The structure of myristoyl-CoA: Protein N-myristoyltransferase. Biochim. Biophys. Acta 1441(2-3), 162-172 (1999).

    2. Martin, D.D.O., Beauchamp, E., and Berthiaume, L.G. Post-translational myristoylation: Fat matters in cellular life and death. Biochimie 93(1), 18-31 (2011).

    3. Darnell, J.C., Osterman, D.G., and Saltiel, A.R. Fatty acid remodelling of phosphatidylinositol under conditions of de novo synthesis in rat liver microsomes. Biochim. Biophys. Acta 1084(3), 279-291 (1991).