A fluorescent probe for cancer cells
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Product Categories

Product Type

Biochemicals
Labeling & Detection
Fluorescent Probes

Research Area

Cancer

Application

Fluorescence

BPN-01

Item No. 39885

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-methoxy-N-(4-(((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)methyl)phenyl)benzo[d]thiazole-2-carboxamide
Molecular Formula
C22H16N6O5S
Formula Weight
476.5
Purity
≥90%
Emission
500 nm
Excitation
475 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/ml
SMILES
COC1=CC=C2C(SC(C(NC3=CC=C(CNC4=CC=C([N+]([O-])=O)C5=NON=C45)C=C3)=O)=N2)=C1
InChi Code
InChI=1S/C22H16N6O5S/c1-32-14-6-7-15-18(10-14)34-22(25-15)21(29)24-13-4-2-12(3-5-13)11-23-16-8-9-17(28(30)31)20-19(16)26-33-27-20/h2-10,23H,11H2,1H3,(H,24,29)
InChi Key
ZOOHPVRNWFEVGB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $72

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    5 mg

    $304

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    10 mg

    $537

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    Cayman Chemical
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    Product Description

    BPN-01 is a fluorescent probe for cancer cells.1 BPN-01 displays an emission maximum of 500 nm upon excitation at 475 nm. It selectively accumulates in DU145 prostate cancer and B16/F10 murine melanoma cells over C2C12 mouse skeletal muscle myoblasts. In vivo, BPN-01 selectively accumulates in tumor tissue over the kidney and liver in an RM-1 prostate cancer mouse xenograft model.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wongso, H., Goenawan, H., Lesmana, R., et al. Synthesis and biological evaluation of new fluorescent probe BPN-01: A model molecule for fluorescence image-guided surgery. J. Fluoresc. 33(5), 1827-1839 (2023).